PO-03-023 OUTCOMES OF LEFT BUNDLE BRANCH AREA PACING AND ATRIOVENTRICULAR NODE ABLATION IN PATIENTS WITH GROUP III PULMONARY HYPERTENSION AND ATRIAL FIBRILLATION IN REDUCING RECURRENT HOSPITALIZATION

Data on the feasibility of left bundle branch area pacing (LBBAP) and atrioventricular node (AVN) ablation in patients with pulmonary hypertension (PH) are limited. This study investigated characteristics outcomes LBBAP AVN PH. is a retrospective PH AF who underwent at Cleveland Clinic between January 1, 2019 August 2022. Pre-procedural, post-procedural, follow-up patient data were obtained. A total 11 (mean age 74±10 years old, 100% female) concomitant included. The etiology was Group III all (55% had COPD 91% restrictive lung disease), average arterial systolic pressure (PASP) 42 mmHg by echocardiogram, FEV1 61.9±17.4% predicted, FVC 59.9±7.8% predicted. Baseline ejection fraction 57±10%, QRS duration 96±20 ms. Concomitant successful patients. Final implant included: 124±8 ms, ventricular activation time 73.7±5.4 ms; threshold 0.6±0.2 mV @ 0.4 ms 0.7±0.2 follow-up; impedance 618±119 ohms 545±145 follow-up. Prior to procedure, number or heart failure (HF) hospitalizations 24 months prior procedure 4.9±5.3, 64% antiarrhythmic drugs, either beta-blockers calcium channel blockers. During mean 21.9±15.3 after HF hospitalization 0.4±0.9, no longer any beta-blockers, There cases lead dislodgement. In elevated PA pressure, good two-year achievable.Tabled 1Pre ablation*Post ablation**P-valueAF hospitalizations4.9 ± 5.30.4 0.9P<0.01On drugs7 (63.6%)0 (0%)P<0.01On rate control drugs11 (100%)0 (0%)NALead dislodgement-0 capture threshold, mV-0.7 0.2NAValues SD n (%) *24 **Average 22±15 Open table new tab